THE INHIBITORY ACTION OF TRI-ORTHO-CRESYL PHOSPHATE ON CHOLINESTERASES
نویسندگان
چکیده
منابع مشابه
The absorption of tri-ortho-cresyl phosphate through the skin of hens and its neurotoxic effects.
General and neurotoxic effects of ingested triortho-cresyl phosphate *(TOCP) in man and animals have been described in detail for the last 20 years. We refer here only briefly to the clinical literature where TOCP was implicated, such as Jamaica ginger paralysis in America (Aring, Bean, Roseman, Rosenbaum, and Spies, 1941; Aring, 1942); the massive intoxications by engine oil at the beginning o...
متن کاملAn outbreak of tri-ortho-cresyl phosphate (T.O.C.P.) poisoning in Durban.
Tri-ortho-cresyl phosphate (T.O.C.P.) is an organic phosphorus compound commonly used in industry as a plasticizer, and is so used in the manufacture of lacquers, dopes, synthetic fabrics, and synthetic lignin resin; it is used as a water-proofing agent in textile manufacture. It is said to be an excellent grinding medium for pigments; it is also used in making polyvinyl chloride sheeting and f...
متن کاملClinical Observation of Acute Delayed Neurotoxicity of Tri Ortho Cresyl Phosphate in Adult Hen
Clinical observation of acute delayed neurotoxicity study for 21 days of organophosphate using triorthocresyl phosphate (TOCP) as a model for organophosphate neurotoxicity, adult hens were dosed by oral gavage with 500mg/kg/bw single dose. Treated hens showed varying degrees of in-coordination, ataxia and paralysis at varying grades and on varying days of treatment mostly depending on the vario...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Pharmacology and Chemotherapy
سال: 1952
ISSN: 0366-0826
DOI: 10.1111/j.1476-5381.1952.tb01321.x